CASE 260: ODDI TUMOR, Dr PHAN THANH HẢI, MEDIC MEDICAL CENTER, HCMC, VIETNAM

Man 40 yo  pain at  RUQ  with  dark urine.

Ultrasound  first   detected  big gallbladder  with  very think wall, no stone, CBD in dilatation just to   end  of CBD, no tumor of  pancreas (2 ultrasound images).

MSCT CE detected  dilated biliary system intra and extrahepatic ( 3 CT images).

Gastro-duodenal  endoscopy  found out a round tumor at Oddi  area (see photo),  biopsy was done.

Blood tests, CEA, CA-19-9 were normal.

What is  your suggestion for   diagnosis and your next step ? 

ERCP not successful.

Biopsy of the tumor but the microscopic result was negative.

Ooen operation for exploration, surgeon detected a hard massat the head of pancreas.

Whipple operation was performed  (specimen of tumor of Oddi).

Microscopic report was  adenocarcinoma ( patho images)

REFERENCE  from Meditoons

CASE 259: PLEURAL EFFUSION, Dr PHAN THANH HẢI, MEDIC MEDICAL CENTER, HCMC, VIETNAM

Woman  23 yo  for one  month cough  and  dyspnea, no  fever.

Ultrasound of the thorax detected left  pleural  effusion with collapsed lung and  one mass covered  anterior mediastinum to external pericardium (see 3 ultrasound pictures of the left lung).

 

MSCT  with CE of   the  chest confirmed a  big  mediastinal  tumor   with  pleural effusion  which displaced  the heart to the right side (see 3 CT pictures).

Blood test and all  cancer markers  were normal. 

Transthoracic biopsy of this tumor with  ultrasound guided for immuno-histochemitry staining . Pathology report is  B CELL  LYMPHOMA.

This  patient is  going to treat with chemotherapy.

REFERENCE:   Mediastinal Tumor

CASE 258: MALIGNANT G I S T RECURRENCE, Dr PHAN THANH HẢI, MEDIC MEDICAL CENTER, HCMC, VIETNAM

Man 54 yo,  2 years after operation for  acute obstruction of small  bowel by  tumor of  intestine, unknown microscopic  report.

Now he had  pain in the pelvis. (photo of  the skin scar operation).

Ultrasound  report   was  multiple  nodules  in  pelvis  looked like  grappe fruit

adherence  over  urinary bladder wall (2 ultrasound pictures).

MSCT CE of abdomen  detected   multiple  intramesenteric round tumors looked like  lymph nodes.

All blood test  and cancer markers were  normal.

Open laparotomy removed the mass which were  multiple  round tumors  adherent  to  great omentum and pedunculated (see  macro1, 2).

Microscopic report this tumor is  malignant  GIST recurrence.

CASE 257: KNEE PAIN, Dr PHAN THANH HẢI, MEDIC MEDICAL CENTER, HCMC, VIETNAM

 Man 35 yo, 3 days ago, pain  at  right knee  cannot move, fever, no  history  of trauma. Clinical examination of right  knee:  hot and swelling at suprapatellar area (see photo).

Ultrasound first  scanned  at the right  knee, detecting  swelling of the  suprapatella recessus with homogeneous fluid  (2 ultrasound pictures).

MRI  of the  right knee  is  same   picture  report ( T1, T2).

Blood test  confirmed this infectious status  with  rising  WBC and  CRP.

For make sure  the  diagnosis: puncture of  the knee joint with  ultrasound guided..removing  the  yellowish  synovial fluid.

LAB analysis report  were  hight WBC and  negative gram stained bacteria  present in this fluid.

Diagnosis of  this case is acute  bacteria  infection of  the knee  joint, emergency  treated  with  antibotic and analgesic drugs.

DISCUSSION: in acute  case  ultrasound   guided  puncture of the  joint is fast action  for fast  diagnosis.

REFERENCE:

CASE 256: LIVER FUNGAL INFECTION in HIV-INFECTED PATIENT, Dr LÊ ĐÌNH VĨNH PHÚC, Dr VÕ NGUYỄN THÀNH NHÂN, MEDIC MEDICAL CENTER HCMC, VIETNAM

A 30 year-old married woman, suffered from weight loss, fatigue, not fever, not abdominal pain. She has scanned by abdominal ultrasound at a province hospital detecting multifocal lesions in liver. Her doctor thought her liver hemangioma.

At MEDIC center, ultrasound scanning detected multi-hyperechoic masses with regular border, no vascular proliferative, no around liver parenchyma edema, no necrosis fluid, size of 0.5 to 2cm in right and left lobe.

CT Scan of liver was done with many reduced density lesions in the right and left lobe. The lesions were slight contrast enhancement. Some lesions were higher than in the center area.

Blood test with WBC normal, transaminases slight increase, HBsAg negative, anti-HCV negative. The important noticeable result is that anti-HIV positive (ELISA).

The findings of ultrasound, CT Scan and blood test suggested liver fungal infection in HIV-infected patient. This patient was treated with anti-fungal drugs. Fungal infection is a common opportunistic disease in HIV-infected patient. Among the fungal opportunistic infections, Coccidioides immitis and Histoplasma capsulatum are those most likely to involve the liver [1]. Fungal liver abscess diagnosis remains a challenge for diagnostic imaging and clinical.

What is your suggestion of diagnosis?

References:

1.  Anthony S. Fauci; H. Clifford Lane (2010). “Human immunodeficiency virus disease: AIDS and related disorders”. Harrison’s infectious diseases. Mc Graw Hill. p. 847

CASE 255: PERI-BREAST TUMOR, Dr PHAN THANH HẢI-Dr JASMINE THANH XUÂN, MEDIC MEDICAL CENTER, HCMC, VIETNAM

Woman 34yo, in palpation detected herself at RUEQ one mass suspected breast tumor.

Mammography confirmed one mass   with  macrocalcification.. at 1h  site of right  breast with dense tissue (see 2 mammo pictures).

Ultrasound  scanning  at  right  breast  detected  one  hypoechoic ellypsoid mass with size of  3cmx2cm  in major pectoralis muscle, Upon CDI  scan  this mass was  hypovascular, and elastoscan  was  hard tissue, no  axillary  lymph node ( see  ultrasound scan B mode, CDI, elasto).

What is your suggestion of diagnosis ?.

MRI of mammary glands  were  done, this  mass  was  retromammary,  inside  major pectoralis muscle  on right site. The  signal  suggestion was hemangioma (see 2 MRI pictures).

FNAC report was compatible with retromammary hemangioma.

  

Operation removed completly this mass; microscopic report  was  cavernous hemangioma.

 

REF case   pdf.

 

CASE 254: CASTLEMAN DISEASE in COLONIC MESENTERY, Dr JASMINE THANH XUÂN, Dr PHAN THANH HẢI, MEDIC MEDICAL CENTER, HCMC, VIETNAM

A 22 yo female patient with a  mass of right abdomen which was detected by ultrasound check-up and thought to be a mesenteric tumor or a lymph node in mesentery. It was well-bordered and vascular structure without any symptom.

MSCT confirmed the 14x17mm mesenteric tumor in right abdomen with CE enhancement.

Open surgery removed the mass from posterior space of right colonic mesentery.

Microscopic result is a Castleman disease in mesentery,  which is an uncommon lymphoproliferative disorder that may be localized to a single lymph node (unicentric) or occur systemically (multicentric).

It was a  second case at Medic Center.
The first case of Castleman disease  was posted in 2010.
CASTLEMAN DISEASE in RETROPERITONEAL SPACE at MEDIC CENTER